文档介绍：过氧化氢氧化对甲基苯甲醛制备对甲基苯甲酸研究于丽颖1,罗亚楠1*,刘立群2,方圆3(,吉林吉林132022;,吉林吉林132021;,吉林吉林132013摘要[目的]探讨过氧化氢氧化对甲基苯甲醛制备对甲基苯甲酸的工艺条件。[方法]以30%过氧化氢为氧化剂,在碱性条件下氧化对甲基苯甲醛制备对甲基苯甲酸,采用正交试验探讨了对甲基苯甲酸的最佳合成工艺条件,并通过测定熔点、红外光谱表征了目标化合物。[结果]优化的合成条件为:物料摩尔比对甲基苯甲醛ʒ30%过氧化氢=1ʒ6,反应温度为40ħ;氢氧化钾浓度为60%。该工艺条件下,对甲基苯甲酸产率达到91%以上;重复性试验结果显示,%。[结论]为对甲基苯甲酸的工业化生产奠定了基础。关键词对甲基苯甲醛;过氧化氢;对甲基苯甲酸;-6611(201201-00257-02Oxidationofp-methylBenzaldehydetop-methylbenzoicAcidbyH2O2YULi-yingetal(DepartmentofChemistryandPharmacy,JilinInstituteofChemistryTechnology,Jilin,Jilin132022Abstract[Objective]Theaimwastoexploreoxidationconditionsofp-methylbenzaldehydetop-methylbenzoicacidbyH2O2.[Method]Usinghydrogenperoxideasanoxidantcatalyze,p-methylbenzaldehydewasoxidizedintop-methylbenzoicacidunderthealkalinecondition,.[Re-sult]Theoptimaloperationconditionswereasfollowed:themolarratioofp-methylbenzaldehydeand30%H2O2was1ʒ6;thereactiontem-peraturewas40ħ;andtheconcentrationofKOHwas60%.Underthebestreactionconditions,theyieldofp-methylbenzoicacidreachedmorethan91%,andthereproducibilityexperimentresultshowedthattheaverageyieldofp-%.[Conclu-sion]Theresearchlaysafoundationfortheindustrialproductionofp--methylbenzald