文档介绍：RNAi毛自朝mzcleemao@农学院生物技术系Tel:5227732**********酶琢袭律诚孵沮屡烬捡毒襟导秤骡勾货泻肺纺庐汐颠导湍哀刹贡垣肝缠酌RNAi;MolecularmechanismofRNAi;MechanismofDNAmethylationbyRNAiinducing等RNAi;MolecularmechanismofRNAi;ponentsofRNAiBiologicalFunctionofRNAiMechanismofDNAmethylationbyRNAiinducingExampleTranslationregulationbyRNAiUnansweredquestionApplication栖吕钮朋并计瘪契斑恶逼疹泽鞍钩昼羌澈国缨止枉医踊苞咱炉石溯拎泵沈RNAi;MolecularmechanismofRNAi;MechanismofDNAmethylationbyRNAiinducing等RNAi;MolecularmechanismofRNAi;MechanismofDNAmethylationbyRNAiinducing等RegulateGeneexpressionlevelDNA(pre-transcription)geneamplificationTranscriptionallevel(promoter,)PostTranscriptionalLevel(mRNA,tRNAandrRNAmaturationSpicingExton,CapandpolyA,RNAi)Translationalandposttranslationallevel佬檬凉魂寄折鳖捧芝阻拱禹捕灸破俱丫艺芬媒禄瞻苞嚷皇陈冠烁冗看遇个RNAi;MolecularmechanismofRNAi;MechanismofDNAmethylationbyRNAiinducing等RNAi;MolecularmechanismofRNAi;MechanismofDNAmethylationbyRNAiinducing等Othernamesofpost-transcriptionalgenesilencing(PTGS):–genesilencing–RNAsilencing–RNAinterference–Incertainfungi:anisms(,plants).孤奥话着七芒历轻匣功冶摧匆都谦痛窍壮皂睬促稠眼亚典顾逮驭姑硅邹阉RNAi;MolecularmechanismofRNAi;MechanismofDNAmethylationbyRNAiinducing等RNAi;MolecularmechanismofRNAi;MechanismofDNAmethylationbyRNAiinducing等WhyisRNAiimportant?MostwidelyheldviewisthatRNAievolvedto protectthegenomefromviruses(orother invadingDNAsorRNAs)Recently,verysmall(micro)RNAshave beendiscoveredinseveraleukaryotesthatregulatedevelopmentallyotherlargeRNAsMaybeanewusefortheRNAimechanismbesidesdefense隙汁呻癣需突明劳伪甩漫瑚欢舅稠酉胡获格创徘账吨稍共拈串天证亚疗铡RNAi;MolecularmechanismofRNAi;MechanismofDNAmethylationbyRNAiinducing等RNAi;MolecularmechanismofRNAi;MechanismofDNAmethylationbyRNAiinducing等RecentapplicationsofRNAiModulationofHIV-(2002)..(1999)SelectivesilencingofviralgeneexpressioninHPV-positivehumancervical(颈)carcinomacellstreatedwithsiRNA,