置换卤化.ppt

文档介绍：置换卤化?卤素置换羟基(1)卤化剂:HX含P卤化物:PCl3,PBr3,PI3含S卤化物:SOCl2(2)卤化氢置换羟基的反应历程R+ + X- R-XROH + H+ RO+H2 R+ + H2O?(3)卤化亚砜和卤化磷对羟基的置换NC2H5C2H5C2H5OHSOCl2NC2H5C2H5C2H4ClSO2HCl甲苯10~40℃3POCl3HClNNClClClNNFFF环丁砜3NaFClClNNHOOHOH3PCl34Cl2HNNHOOO吡啶POCl3?卤素置换磺酸基OOSO3KSO3KOOClCl+NaClO3+HCl+KHSO4+NaCl?置换氟化?卤化试剂:HF,KF,NaF,AgF,SbF53POCl3HClNNClClClNNFFF环丁砜3NaFClClNNHOOHOH3PCl34Cl2HNNHOOO吡啶POCl3氟利昂-:百位数(C数-1)a:十位数(H数+1)b:个位数(F数)Cl3CF3C+3HF80~140℃17~18kg/cm2+l3F+l4+HF氟利昂-l3+2HFCHClF2+2HCl600~900℃CF2=CF2+l3+3HF3140℃,l2F2-CFCl2+3HCl氟利昂-22氟利昂-113