中枢系统疾病二.ppt

文档介绍：§3 Infections
病因诊断技术
Electron microscope
Immunohistochemistry 免疫组织化学
Hybridization in situ 原位杂交
Cultivation 培养
Immunoassay 免疫检测
PCR 多聚酶链反应
神经系统感染性疾病
I. Acute pyogenic meningitis
急性化脓性脑膜炎
病因
青少年: us 脑膜炎双球菌
发病机制
病人
带菌者
飞沫
呼吸道
上呼吸道
脑膜
血
Epidemic meningitis 流行性脑膜炎(流脑)
局部炎症
病变
Pyogenic inflammation of leptomeninges
软脑膜蛛网膜的化脓性炎
肉眼:脑脊膜血管高度扩张充血,
蛛网膜下腔充满脓性渗出物
光镜:嗜中性白细胞为主的炎细胞浸润
Acute pyogenic meningitis
Here is another example of an acute meningitis from bacterial infection. The cerebrospinal fluid (CSF) in such cases typically has a low glucose, high protein, and many PMN's. A gram stain should be done to anisms.
a gram stain reveals gram negative i within a neutrophil, typical for Neisseria meningitidis. Gram stain and culture can be performed on cerebrospinal fluid obtained via lumbar puncture. A variety of bacteria can cause meningitis, but several are mon, and have an incidence more frequent at certain ages:
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临床病理联系
颅内压增高
脑膜刺激症状
脑脊液变化
结局和后遗症
脑膜粘连
颅神经受损
Acute pyogenic meningitis