文档介绍：旋光度法测定盐酸麻黄碱滴鼻液的含量(1)    】目的用旋光度法替代酸碱滴定法测定盐酸麻黄碱滴鼻液的含量。方法分别用旋光度法与酸碱滴定法测定盐酸麻黄碱滴鼻液的含量,并将其结果进行比较。%~%(g/ml)浓度之间线性关系良好(r=),平均回收率(n=9)%,RSD=%;与酸碱滴定法所测得样品结果经统计学检验,差异无显著性。结论旋光度法简便、快速、准确,可用于盐酸麻黄碱滴鼻液的含量测定。    【关键词】盐酸麻黄碱滴鼻液;旋光度法;含量测定    Determinationofephedrinehydrochloridenasaldropsbypolarimetry    DINGHui-ping,HUANGPing,PANYong,,Changsha410006,China    【Abstract】ObjectiveTodeterminatethecontentofephedrinehydrochloridenasaldropsbypolarimetryinsteadofacid---%~%(g/ml)(r=).%(n=9)withRSD=%.Thedifferenceofthedataobtainedbypolarimetryandacid-,urateforthedeterminationofthecontentofephedrinehydrochloride,andcanbeusedasanalternativemethodofacid-basetitrationstodeterminateephedrinehydrochloridenasaldrops.    【Keywords】ephedrinehydrochloridenasaldrops;polarimetry;contentdetermination    《中国医院制剂规范》第2版[1]收载的“盐酸麻黄碱滴鼻液”处方组成为“盐酸麻黄碱10g,氯化钠6g,,蒸馏水加至1000ml”。其中含盐酸麻黄碱()1%,含量测定方法采用酸碱滴定法,而该书收载的“复方呋喃西林滴鼻液”中盐酸麻黄碱的含量测定采用旋光度法,旋光度法较酸碱滴定法简便快速,准确可靠。为验证旋光度法测定“盐酸麻黄碱滴鼻液”含