文档介绍：,苏赞郑州大学第三附属医院药剂科郑州市450052?11?摘要目的研究蛤蚧定喘分散片的止咳祛痰,,给药后分别考察小鼠对氨水,,祛痰的实验研究表明,,1,65g/kg两个剂量组能明显延长小鼠氨水引起的咳嗽潜伏期和减少咳嗽次数(P<).(P<).蛤蚧定喘分散片0,54g/kg,(P<).豚鼠平喘实验表明,,】哮喘反应,潜伏期明显延长(P<).最大耐受量相当于***,平喘作用.***;止咳;祛痰;平喘;最大耐受量中图分类号:R一332文献标识码:A文章编号:1672—3422(2008)10~011-03StudyonPharmacodynamicsandToxicologyofHajieDingchuanDispersibleTabletsLIHong,SUZanThe3thHospitalofZhengzhouUniversity,Zhengzhou450052,ChinaABSTRACTObjectiveResearchingforrelievingacoughandremovingthephlegmandre—,afterdealingwithdrug,thereactionsofthemiceforammoniaand~—perimentofrelievingacoughandremovingthephlegmshowthattwodosegroups(,)ofhajiedingchuandispersibletabletsnotabilitycanextenddelitescenceofcoughformicewhichinducedbyammoniaandreducedegreesofcough(P<).Comparingwithdingchuanpills,(,)tabletsnotablyincreaseexudationof~nho