文档介绍：Medicinal es M. Halpern, MD, PhDDistinguished Professor of Pharmaceutical Sciences Hong Kong Polytechnic University ******@Chinese Translation by Dr. Sammi Tsui [ABCT]?Primary Structure of BG一级结构Secondary二级结构Tertiary三级结构Importance of Tertiary Structure? The Transistor is the Primary Structure? The Circuit Board is the Secondary Structure? puter is the Tertiary Structure~ In Electronics ~Terpenoids in Mushrooms菌体中的萜类化合物?Anti-infectious 抗感染?Anti-inflammatory 抗炎Medicinal Mushrooms and Prebiotics药用菌与益生元?Mushrooms form a class above many other prebiotics 菌高于其它许多益生元类?Stimulate M cells in the lining of the intestine 刺激在肠衬里的M细胞Ganoderma lucidum (Reishi, Lingzhi) 灵芝Bitter (terpenoids)苦(萜类)Traditional indications: CFS,传统指标: CFSDiabetes,↑cholesterol, Asthma 糖尿病, ↑胆固醇,哮喘Vit C improves absorption提高维生素C的吸收Protects skin vs. UV (cancer), WBC vs. TNF-α, IL-1β, IL-6 to upper limit of normal (vs. cancer??)提升肿瘤坏死因子-α,白介素1β,白介素6 的水平(抗癌?)IFF Benzie‘Bioavailability’ requires…–Absorption–Distribution to site(s) of utilization (via blood plasma)–Active form to be present in viable amounts at these sitesIFF BenzieIn VivoStudy to Assess ‘Bioavailability’of Antioxidants in Green Tea, and Ganoderma lucidum (Lingzhi)?Acute post ingestion (up to 3h; placebo-controlled)*, n= g, n=7Photo courtesy of NAMMEX400 ml strong green tea?BloodcollectedUrine collectedAgentingestedIFF BenzieBioavailability of Lingzhi (Ganoderma lucidum) Antioxidants* significantly (P<) different from time-matched level after placebo# significantly (P<) different from pre-ingestion valueWachtel-Galor, Tomlinson, Benzie. Int J Food Sci Nutr 2004;1:75-83