文档介绍：
鹅掌柴脂溶性成分的研究#
刘祥,欧阳明安,任青云**
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(福建农林大学生物农药与化学生物学教育部重点实验室,福州,350002)
摘要:鹅掌柴 S. octophylla(Lour.)Harms 为五加科鹅掌柴属植物,在我国东南和西南地区
均有分布。叶、根皮和树皮可作药用,具有祛风止痛、舒筋活络、发汗解表、活血消肿等作
用,该属植物所含主要为三萜类化合物,另外还有甾体化合物、挥发油、长链烯烃、有机酸、
偶氮、寡糖、醌类等化学成分。前人研究主要集中在庭院栽培和蜜源开发利用上,而对有效
成分的研究还很少,为推动新型药物的开发和利用,本文以采自泉州清源山的鹅掌柴为研究
对象,综合利用正相硅胶柱,Rp-18 类反相柱和 HPLC 等方法从其脂溶性部分中分离到 6 个
化合物(1-6),根据波谱数据分别鉴定为β-谷甾醇(1),豆甾醇(2),4, 22-二烯-3-
酮豆甾烷(3),24, 25-二甲基-5-胆甾烯(4),1β, 3β, 23-三羟基-12-乌苏烯-28-O-
α-L-吡喃鼠李糖-(1→4)-β-D-吡喃葡萄糖-(1→6)-β-D-葡萄糖苷(5),9-十八碳烯酸甲
酯(6)。
关键词:鹅掌柴;化学成分;分离;结构鉴定
中图分类号:
Studies on the fat-soluble constituents of Schefflera.
octophylla (Lour.) Harms
LIU Xiang , OUYANG Ming-an , REN Qingyun
(Key Laboratory of Bio-Pesticide and Chemistry-Biology, Ministry of Education, Fujian
Agriculture and Forestry University,Fuzhou,350002)
Abstract: S. octophylla(Lour.) Harms of genus Schefflera(Araliaceae family), is widely
distributed such as southeast and southwest areas of China. Its leaves and barks are used as
medicine with the functions of dispelling wind and relieving pain, relaxing tendons and collaterals,
inducing diaphoresis, activating blood circulation and detumescence. The genus contains mainly
triterpenoids, in addition to steroids, volatile oil, long chain olefins, organic acids, azo,
harides, quinones and other chemical ingredients. The previous studies mainly
con