文档介绍:(:2003------------------------INDICATIONSANDUSAGE-------------------------NAMENDAXRcontainsmemantineHCl,anNMDAreceptorantagonistindicatedforthetreatmentofmoderatetoseveredementiaoftheAlzheimer’stype.(1---------------------DOSAGEANDADMINISTRATION-------------------InitialDose7mgNAMENDAXRoncedaily((.(.(-------------------DOSAGEFORMSANDSTRENGTHS-----------------NAMENDAXRisavailableasanextended-releasecapsule(:7mg,14mg,21mg,28mg(,:CONTENTS*--------------------------------CONTRAINDICATIONS------------------------------NAMENDAXRiscontraindicatedinpatientswithknownhypersensitivitytomemantinehydrochlorideortoanyexcipientsusedintheformulation.(------------------------WARNINGSANDPRECAUTIONS-----------------------ConditionsthatraiseurinepHmaydecreasetheurinaryeliminationofmemantineresultinginincreasedplasmalevelsofmemantine.(---------------------------------ADVERSEREACTIONS----------------------------urringatafrequencyofatleast5%andgreaterthanplacebowithadministrationofNAMENDAXR28mg/daywereheadache,.(6ToreportSUSPECTEDADVERSEREACTIONS,ContactForestLaboratories,-800-678-1605orFDAat1-800-FDA-1088orwatch.---------------------------------DRUGINTERACTIONS-----------------------------UsewithotherNMDAantagonists(amantadine,ketamine,anddextromethorphanhasnotbeensystematicallyevaluatedandsuchuseshouldbeapproachedwithcaution.(------------------------USEINSPECIFICPOPULATIONS-----------------------PediatricUse:Thesafetyand