文档介绍：局部晚期鼻咽癌TP方案诱导化疗及同期放化疗初步观察【摘要】目的:观察局部晚期鼻咽癌诱导化疗及不同化疗方案的依从性及不良反应。方法:将60例局部晚期鼻咽癌患者按照随机数字表法分为A、B、C三组,A组TP诱导化疗+同期顺钳放化疗,B组顺钳同期放化疗,C组TP同期放化疗。放疗为调强放疗,GTVnx68〜72Gy,GTVnd65〜70Gy。观察三组治疗依从性及不良反应情况。结果:%>%、%,放疗全部足量完成,依从性均好,最常见反应为胃肠道反应、口咽黏膜炎、骨髓抑制、皮肤损伤,三组比较差异均无统计学意义(P>)o但同时中重度不良反应发生率A组最高,B组最低,差异有统计学意义(P【关键词】局部晚期鼻咽癌;同期放化疗;诱导化疗;不良反应PreliminaryResearchofTP-basedInductionChemotherapyandConcurrentChemotherapyintheTreatmentofLocallyAdvancedNPC/LIJin-wei,XIAOHai,WANGRong,etal.//MedicalInnovationofChina,2016,13(27):010-013【Abstract】Objective:Toobservetheadherenceandadversereactionsofinductionchemotherapyanddifferentconcurrentchemotherapyregimensforlocallyadvancednasopharyngealcarcinoma(NPC)・Method:Atotalof60patientswithlocallyadvancedNPCwererandomlydividedintoA,B,Cgroups,-basedinductionchemotherapy,followedbyconcurrentchemoradiotherapywithcisplatin;GroupBwasgivenCisplatin--,GTV