肿瘤血管生成与超声造影成像相关性研究进展.pdf.pdf

文档介绍：466·生旦医学影堡蕉!笙星鲞塑塑ChinJMedImagingTeehnol,2007,Vol23,No3Advancesofcorrelationsbetweentumorangiogenesisandcontrast—enhancedultrasoundJ1,4NGHo,g~]l11(2‘(1h(,川,ff)M￡,(7(’口fUlt口?f『J‘i(、d,“￡('ent,.川?』卜￡,,7川w,tKt、『l,、-“/f’fJ/fl、7f_l?(、m.￡?,“1【_,¨1.(、洲、[Abstract]Angiogenesisisthecharaclerofmalignanttumors,microxasculardensit3’isnoton13,thegoldstandardto【1、,aluatetumorangiogenesis,—enhanceduhrasoundisone0fthelatestmethodStoevaluatetumorangiogeneslsatpresent,,theindex—evaluatedangiogenesishasasignificantcorrelationwithmicrovasculardensitySocontrast—enhancedultrasoundcanhelppredictprognosisandselecttrcatillCil[plan)faI1tianElL~gcnict1)ciap\d11{ttxailtistt11Ke)、’or(Is(1¨tI8SI—tgllllallCtdLlhIasound;esis;hIicl叭asculaldensiD;Vast'tlld~lendoflkdialglm、lhlaclof肿瘤管毕与韶吉诰影像相苹悻石弭蜜讲羼?·H—‘)[摘要],可通过测定各种灌注参数对活{、手术切除等治疗方案的选择提供重要的依据。[关键词]超声造影;血管生成;微血管密;血管内皮生长因子[中图分类号];[文献标识码]A[文章编号]1003—3289(2007)03-0466—032O世纪7O年代初,Folkman首先提出“肿瘤生长和转移都依赖于新生血管的形成”的概念[1],并得到大量实验结果的证实,目前这一概念已经形成共识。血管生成(angiog