文档介绍：TETRAHEDRON
Pergamon Tetrahedron 57 82001) 9199±9223
Tetrahedron report number 588
A tentative rationalization of microwave effects
anic synthesis according to the reaction medium,
and mechanistic considerations
Laurence Perreux and Andre Loupyp
Laboratoire des ReÂactions SeÂlectives sur Supports, ICMO, Universite Paris-Sud, CNRS, UMR 8615, BaÃtiment 410,
91405Orsay cedex, France
Received 17 July 2001
Contents
of microwave effects 9200
®c microwave effects 9202
effects 9202
according to reaction mechanisms 9204
. Isopolar transition state reactions 9204
. Bimolecular reactions between neutral reactants leading to charged products 9205
. Anionic bimolecular reactions involving neutral electrophiles 9205
. Unimolecular reactions 9206
according to transition state position along the reaction coordinates 9206
on selectivities 9207
illustrative examples 9207
. Bimolecular reactions between neutral reactants 9207
. Nucleophilic additions to pounds 9207
. Imine or enamine synthesis 9207
. Hydrazone synthesis 9208
. Amidation of carboxylic acids 9208
. Synthesis of 2-oxazolines 9208
. Synthesis of aminotoluenesulfonamides 9208
. Synthesis of alkyl p-toluenesul®nates 9209
. Leuckart reductive amination of pounds 9209
. Michael additions 9209
. SN2 reactions 9210
. Reaction of pyrazole with hyl bromide 9210
. Ring opening of an epoxide by amines 9210
. N-alkylation of 2-halopyridines 9210
. Nucleophilic aromatic substitutions 9210
. Synthesis of phosphonium salts 9211
. Bimolecular reactions with one charged reactant 9211
. Anionic SN2 reactions involving charge localized anions 9211
. Selective dealkylation of aromatic pounds 9211
. Alkylation of dianhydrohexitols under PTC conditions 9212
.