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外刊外报阅读.doc

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文档介绍:Passage1AIDStreatmentVisconti’scoupMar14th2013,21:(thenameisacontractionof“Virologicalandimmunologicalstudiesincontrollersaftertreatmentinterruption”),beingconductedinFrance,—-termremissionmaybepossibleforasmanyas15%,reportedinthePublicLibraryofScience’sjournalPLoSPathogensbyChristineRouziouxofParisDescartesUniversityandhercolleagues,hasfollowedthefatesof14peopletreatedwithantiretroviraldrugsshortlyaftertheywereinfectedwithHIV,andforseveralyearsthereafter,whothen(undermedicalsupervision)’sorganisersreportedtotheInternationalAIDSConferenceinWashington,lastJuly,thisprocedurehasturnedthesepeopleintowhatareknownas“elitecontrollers”—thatis,theystillhavedetectablelevelsofHIVintheirbodiesyearsafterinfection,butevenintheabsenceofdrugtreatmentthoselevelsdonotrisesignificantly,,,butcertainversionsofwhatareknownasHLAgenes(whichregulatecell-surfaceproteinsinsomeimmune-systemcells),,itdidsoearlyandaggressively(onereasonwhytheyweretreatedsoquicklyinthefirstplace).Yet,afteranaverageofthreeandahalfyearstakingantiretroviraldrugs,followedbyanaverageofsevenandahalfyearsnottakingthem,,thepapersuggests,eventhelowlevelsofvirusstillcirculatingintheirbodiesseem,insever