文档介绍：Preparation and Evaluation of the granule of Xiaozhitongmai. Speciality : Pharmacy of TCM Author: Ma Qiuju Tut or: Weiping o Abstract Objective: The Preparation and Evaluation of pound Chinese medicine Xiaozhitongmai. Methods : We extracted the volatile oil from Curcuma and Atractylodes macrocephala and Citri reticulatae by the Supercritical CO2 Flui d the yield of volatile oil as index ,we selected the Optimum extraction conditions by the orthogonal test, which were 25MP a(the extracting pressure), 45 ℃(the extracting temperature ) ,(the extracting time). Us ing the ultizision ratio of oil and the oil-beared ratio and the yield of pound as indexe s , we selected the Optimum conditions for inclusion by the orthogonal test ,which were 1:8(w/w) (the ratio of oil β-CD ), 50 ℃(the inclusion temperature),1hour(the inclusion time).To find the best condition of extracting the active constituents of Xiaozhitongmai Granule with alcohol, using the yield of alcohol extractive and content of AlisoB23-acet ate as the detective indexes,we selected Optimum extracting c onditions by The orthogona l text. Experiments showed best condition was Volume ratio of 1:8( w/w) (the ratio of herbs and 70% alcohol), extracting for 2 times(first times 60min,sec ond times 30 min) and water temperature was 50 ℃.Extracting solu tion with alcohol was Concentrated by pressure-reduced distillation and dried in Vacuum dry box. a nd water-content of alcohol ex tractive was smaller than 4%. in the Preparation Process ,Coix lachrymajobi was used as Cppropriate ,Steviosin was used to correct the taste and 80% alcohol was us ed as moistening carried out the dctermination methods of Pinellia Ternata 、WeiLing- Xian 、 Rhubarb 、Curcuma and Atractylodes macrocephala through TLC ,and the speekles were clear and the negative contrast had no content of AlisoB23-acetate and Hesperidi was determined through HPLC in X