文档介绍：8 | VO LUM E 34 | NUMB ER 1 | FE B R UA R Y 2011 lgesics and pain relief in pregnancy and breastfeeding Debra Kennedy , Director, MotherSafe, Royal Hospital for Women, and Conjoint Lecturer, School of Women's and Children's Health, University of New South Wales, Sydney Summary Women should be reassured that pain can be treated during pregnancy and lactation and that they need not suffer unnecessarily. Overall, appropriate therapeutic doses of monly used analgesics including paracetamol, aspirin and opioids have not been associated with an increased incidence of birth defects. The use of non-steroidal anti-inflammatory drugs in the third trimester is not mended. Untreated persistent pain can have adverse effects for the mother and her pregnancy and women with persistent pain should ideally have optimisation of their pain management before pregnancy. Key words: codeine, non-steroidal anti-inflammatory drugs, opioids, paracetamol. (Aust Prescr 2011;34:8–10) I ntroduction Pain during pregnancy may be due to acute conditions such as injury or infection, or secondary to underlying medical disorders such as rheumatoid arthritis. Pain related to pregnancy can also occur. Inadequately managed persistent pain can result in depression and anxiety. These may impact on a woman's physical and psychological wellbeing and can potentially have an adverse effect on her pr