文档介绍：治疗询后检测高危型HPV的临床价值【关键词】治疗【摘耍】目的研究重度宫颈上皮内瘤变(CIN)中高危型人乳头瘤病毒(HPV)感染情况,及术前与术后高危型HPV检测对预后的意义。方法门诊细胞学联合HPV检测,筛杳出72例经病理诊断为CIN2-3患者,采用电圈切除术(LEEP)治疗,术后每半年随访,包括汀CT,HPV,***镜。***镜检查有异常或HSIL者行活检,病理证实为CIN2-3以上视为病变残留或复发。结果63例治愈,%。9例(%)复发或残留。72例患者中,58例HPV阳性,%,%,%显著升高。,差异尤显著性。而术后高危型HPV检测残留或复发有较高的灵敏度和阴性预测价值。结论高危型HPV在重度CIN中感染率高,但术前高危型HPV与预后无关,术后高危型HPV检测预测残留或复发有重要价值。【关键词】宫颈上皮内瘤变;电圈切除术;人乳头瘤病毒ValueofHPV-jDNAtestbeforeandafterLEEPofCINindetectionofprognosisTANYi,LIJie,XIEPing,etal.(DepartmentofGynecology,NanchengHospital,Dongguan,Guangdong523700,China)[Abstract]herateofHPVinfectionincervicalintraepithelialneoplasia(CIN)andtoevaluateHPV--callyconfirmedCIN2/3werefollowed-upbiannuallyincludingcervTicalcytology,hybridcaptureII(HCID,-tientspresentingabnormalcolposcopyorhigh-gradesquamousintraepitheliallesion(HSIL)smearweresubjectedtonewexcisionprocedure,andpresenceofhistologicallyconfinnedCIN2/(%)womenshowedresidualorrecurrenceofdiseaseduringthefoIlow-%.%inCIN3wassignificantlyhigherthanthatinCIN2(%,P<)・