文档介绍：Article 1136 Am J Psychiatry 165:9, September 2008 ajp. This article is featured in this month’s AJP Audio and is discussed in editorials by Dr. Reiss (p. 1083) and Dr. Markowitz (p. 1086). Children of Depressed Mothers 1 Year After the Initiation of Maternal Treatment: Findings From the STAR*D-Child Study Daniel J. Pilowsky, ., . Priya Wickramaratne, . Ardesheer Talati, . Min Tang, . Carroll W. Hughes, . Judy Garber, . Erin Malloy, . Cheryl King, . Gabrielle Cerda, . A. Bela Sood, . Jonathan E. Alpert, ., . Madhukar H. Trivedi, . Maurizio Fava, . A. John Rush, . Stephen Wisniewski, . Myrna M. Weissman, . Objective: Maternal depression is a con- sistent and well-replicated risk factor for child psychopathology. The authors ex- amined the changes in psychiatric symp- toms and global functioning in children of depressed women 1 year following the initiation of treatment for maternal major depressive disorder. Method: Participants were 1) 151 women with maternal major depression who were enrolled in the Sequenced Treatment Alternatives to Relieve Depres- sion (STAR*D) study and 2) their eligible offspring who, along with the mother, participated in the child STAR*D (STAR*D- Child) study (mother-child pairs: N=151). The STAR*D study was a multisite study designed to determine parative effectiveness and acceptability of various treatment options for adult outpatients with nonpsychotic major depressive dis- order. The STAR*D-Child study examined children of depressed women at baseline and involved periodic follow-ups for 1 year after the initiation of treatment for maternal major depressive disorder to as- certain the following data: 1) whether changes in children’s psychiatric symp- toms were associated with changes in the severity of maternal depression and 2) whether es differed among the offspring of women who did and did not remit (mother-child pairs with follow-up data: N=123). Children’s psychiatr