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Lung Mechanics
With mathematical putational models furthering our understanding of lung
mechanics, function, and disease, this book provides an all-inclusive introduction to
the topic from a quantitative standpoint. Focusing on inverse modeling, the reader is
guided through the theory in a logical progression, from the simplest models up to
state-of-the-art models that are both dynamic and nonlinear.
Key tools used in biomedical engineering research, such as regression theory, linear
and nonlinear systems theory, and the Fourier transform, are explained. Derivations of
important physical relationships, such as the Poiseuille equation and the wave speed
equation, from first principles are also provided. Examples of applications to experi-
mental data illustrate physiological relevance throughout, whilst problem sets at the end
of each chapter provide practice and test prehension. This book is ideal for
biomedical engineering and biophysics graduate students and researchers wishing to
understand this emerging field.
Jason H. T. Bates is currently a Professor of Medicine and Molecular Physiology and
Biophysics at the University of Vermont College of Medicine, and a Member of the
Pulmonary Division at Fletcher Allen Health Care. He is also a Member of the American
Physiological Society, the American Thoracic Society, and the Biomedical Engineering
Society, and an elected Senior Member of the IEEE Engineering in Medicine and Biology
Society. Dr. Bates has published more than 190 peer-reviewed journal papers in addition
to numerous book chapters, conference abstracts, and other articles. In 1994 he was
awarded the Doctor of Science degree by Canterbury University, New Zealand, and in
2002 he was elected a Fellow of the American Institute for Medical and Biological
Engineering.
Lung Mechanics
An Inverse Modeling Approach
University of Vermont
CAMBRIDGE UNIVERSITY PRESS
Cambridge, New York, Melbo