文档介绍：e Each of You to My Molecular Biology Class
Molecular Biology of the Gene, 5/E --- Watson et al. (2004)
Part I: Chemistry and ics
Part II: Maintenance of the Genome
Part III: Expression of the Genome
Part IV: Regulation
Part V: Methods
3/22/05
Part V: Methods
Ch 20: Techniques of Molecular Biology
Ch 21: anisms
CHAPTER 21
anisms
Molecular Biology Course
anisms
Fundamental problems are solved in the simplest and most accessible system in which the problem can be addressed.
anisms are called anisms.
Some Important anisms
Escherichia coli and its phage (the T phage and phage λ)
Baker’s yeast haromyces cerevisiae
The nematode Caenorhabditis elegans
The fruit fly Drosophila melanogaster
The house mouse Mus musculus
Features of Model Systems
The availability of powerful tools of traditional and molecular ics.
The study of each model system attracted a critical mass of investigators. (Ideas,methods, tools and strains could be shared)
HOW to choose a anism?
It depends on what question is being asked. When studying fundamental issues of molecular biology, simpler anisms or viruses are convenient. For developmental questions, anisms should be used.
Model 1: BACTERIOPHAGE
CHAPTER 15 The ic Code
5/08/05
Bacteriophage (Viruses)
The simplest system
Their genomes are replicated only after being injected into a host cell.
The genomes can bine during these infections.