文档介绍：手术切口感染病原菌分析及管理策略手术切口感染病原菌分析及管理策略首席医学网作者:高新云,罗晓明,施安娜,何坤作者单位: ( 解放军第 161 中心医院,湖北武汉 430010) 【摘要】目的探讨手术切口感染的病原菌及药物敏感性,制定相应的管理策略,为控制医院感染提供参考。方法回顾性分析某院 4 335 例外科手术患者切口感染情况, 收集伤口分泌物进行细菌培养及鉴定, 对培养细菌进行药物敏感性分析, 并制定相应的手术室管理策略。结果 4 335 例外科手术患者发生切口感染 189 例次检出致病菌 162 株,其中 G 杆菌占 % ,其中主要为大肠埃希菌占 % 、肺炎克雷伯杆菌占 % 、铜绿假单胞菌占 %;G+ 球菌占 %; 真菌占 % 。药敏分析发现 G 菌对亚***培南最为敏感, 而对青霉素、庆大霉素、头孢氨苄、克林霉素等的耐药率均超过 50% 。 G+ 菌对亚***培南、万古霉素敏感性强, 对其他抗生素均有较高的耐药性。结论手术切口感染病原菌多以 G 菌为主, 并且具有较高的耐药性, 必须采取合理的管理策略,预防感染发生。【关键词】手术切口感染; 细菌培养; 药物敏感性; 管理 Abstract : Objective To explore the bacteriology and drug sensitivity of operative incision infection and to construct corresponding management strategy in order to provide references for controlling hospital infection. Methods The operative incision infections of4 335 patients who underwent surgery were analyzed retrospectively. Incision secretion was collected, bacteria culture was performed and pathogen identification as well as drug sensitivity analysis was done. Meanwhile, corresponding management strategy was constructed. Results Of the 4 335 patients who underwent surgery, 189 patients had operative incision infection with a total of 162 strains of bacteria. The pathogenic bacteria were majored in G bacillus (79%) including colibacillus(%), klebsiella pneumoniae(%)and pseudomonas aeruginosa(%). G+ obacteria accounted for % and fungus accounted for