文档介绍：By Atta-ur- Rahman, University of Karachi, Karachi, Pakistan
Muhammad Choudhary, University of Karachi
Contents
The Basics of Modern NMR Spectroscopy:
What is NMR? Instrumentation. Creating NMR Signals.
Spin-Echo and Polarization Transfer:
Spin-Echo Formation in Homonuclear and Heteronuclear Systems. Cross-Polarization.
Polarization Transfer in Reverse.
The Second Dimension:
Data Acquisition in 2D NMR. Data Processing in 2D NMR. Plotting 2D Spectra.
Nuclear Overhauser Effect:
nOe and Selective Population Transfer. Relaxation. Mechanism of nOe. Factors Affecting
nOe. Some Practical Hints.
Important 2D NMR Experiments:
Homo- and Heteronuclear J-Resolved Spectroscopy. Homonuclear and Heteronuclear Shift-
Correlation Spectroscopy. Two-Dimensional Nuclear Overhauser Spectroscopy. Two-
Dimensional Chemical Exchange Spectroscopy. Homonuclear Hartmann-Hahn Spectroscopy
(HOHAHA), or Total Correlation Spectroscopy (TOCSY). Inverse NMR Spectroscopy.
Inadequate.
The Third Dimension:
Basic Philosophy. Types and Positions of Peaks in 3D Spectra.
Recent Developments in NMR Spectroscopy:
Selective Pulses in Modern NMR Spectroscopy. One-Dimensional Experiments Using Soft
Pulses. Heteronuclear Selective 1D NMR Experiments. Two-Dimensional Experiments Using
Soft Pulses. Soft Excitation in Two Dimensions. Three-Dimensional Experiments Using Soft
Pulses. Field Gradients.
Logical Protocol for plex Structural Problems: 3-Hydroxylupanine. (1).
(+)-Buxalongifolamidine.
(2).
References. Subject Index.
Foreword
The past twenty years have witnessed the development of nuclear mag-
netic resonance (NMR) into one of the most powerful analytical tools of
natural science. Applications range from solid state physics to chemistry,
biology, and medicine. NMR takes advantage of the presence of nuclear
spins inserted by nature at strategic points in virtually all materials and
anisms. NMR has e not only one of the most useful
but also one of the most sophist