文档介绍:食管癌化疗方案 艾迪注射液联合同步放化疗治疗食管癌的临床观察
摘 要 目的:观察艾迪注射液联合同步放化疗治疗食管癌的疗效和不良反应。方法:收治食管癌患者62例,随机分为两组,艾迪注射液组(A组)31例采用艾迪注射液联合同步放化疗的方法;对照组(B组)31例采用单纯同步放化疗的方法。艾迪注射液组中艾迪注射液80ml+NS 400ml,d1~d14/周期。治疗期间每周观察骨髓抑制、放射性食管炎、消化道反应等不良反应。同步放化疗结束后2周观察患者机能状态及免疫功能。放化疗后3个月、12个月评价有效率(CR+PR)。结果:艾迪注射液组和对照组总有效率分别为9355%和8710%(P>005)。对照组不良反应大于艾迪注射液组,骨髓抑制、胃肠道反应及放射性食管炎发生率差异有显著性(P<001)。结论:艾迪注射液联合同步放化疗治疗食管癌能减轻放化疗的不良反应,提高肿瘤患者的生存质量,并能提高有效率。
关键词 艾迪注射液 食管癌 同步放化疗
doi:.1007-
Abstract Objective:to observe the eddy injection joint chemoradiation treatment in patients with cancer of the esophagus efficacy and side :the March 2008~2009 12 menstrual pathology esophageal for 62 cases of patients,randomly divided into two groups:eddy injection group(group
A)31 cases by the eddy injection chemoradiation joint the method;The control group(group B)31 cases by the simple method of chemoradiation injection group eddy injection 80 ml+NS 400ml,d1~d14/ week during treatment of bone marrow suppression,observe radioactive esophagitis,gastrointestinal reaction and other side weeks after the chemoradiation observe patients functional status and immune and chemotherapy after 3 months,12 months evaluation efficient(CR+PR).Results:eddy injection group and control group total effectiveness % and %,respectively(P>005).The con