文档介绍：埃索美拉唑与奥美拉唑治疗反流性食管炎的随机对比研究
 
   
 
 
 
 
 
 
 
     
 
 
 
 
 
[摘要]目的 对反流性食管炎患者应用埃索美拉唑与奥美拉唑的治疗效果进行对比探究。方法 选取2019年1月~2020年12月到我院接受治疗的50例反流性食管炎患者作为此次实验研究对象，依据随机数字法将50例患者均分为两个小组（对照组25例，予以奥美拉唑治疗；研究组25例，予以埃索美拉唑治疗），对两组的治疗效果、临床症状积分和不良反应发生率进行对比。结果 对照组中有7例（%）患者治疗无效，%（18/25），研究组中仅有1例（%）患者治疗无效，治疗有效人数为24，%，比对照组高（P<）；经治疗后，对照组与研究组患者症状积分分别是（±）分、（±）分，与治疗前相比均有所下降，其中研究组下降幅度更大，明显低于对照组（P<）；研究组中有1例（%）患者出现乏力，%，对照组1例（%）头晕、2例（%）腹泻，%，高于研究组，但两组差异较小（P>）。结论 埃索美拉唑治疗反流性食管炎效果更显著，患者临床症状有明显改善，且不良反应少，应用价值高，可作为临床反流性食管炎的理想治疗药物。
[关键词]埃索美拉唑；奥美拉唑；反流性食管炎；治疗效果
[Abstract] Objective To compare the efficacy of nexomeprazole and omeprazole in the treatment of patients with reflux esophagitis. Methods A total of 50 patients with reflux esophagitis who received treatment in our hospital from January 2019 to December 2020 were selected as the experimental research objects. According to random number method, the 50 patients were pided into two groups (control group, 25 cases were treated with omeprazole; In the study group, 25 patients were treated with esomeprazole), and the therapeutic effect, clinical symptom score and the incidence of adverse reactions were compared between the two groups. Results In the control group, 7 cases (%) were ineffective and the total effective rate was % (18/25). In the