文档介绍：FEBS Letters 583 (2009) 3959–3965
journal homepage:
Review
Fungal regulatory evolution: cis and trans in the balance
Dawn Anne Thompson a, Aviv Regev a,b,*
a Broad Institute of MIT and Harvard, 7 Cambridge Center, Cambridge, MA 01242, United States
b Howard Hughes Medical Institute, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 01240, United States
article info abstract
Article history: Regulatory divergence is likely a major driving force in evolution. Comparative genomics is being
Received 15 October 2009 increasingly used to infer the evolution of gene regulation. Ascomycota fungi are uniquely suited
Revised 9 November 2009 among eukaryotes for regulatory evolution studies, due to broad phylogenetic scope, many
Accepted 10 November 2009
sequenced genomes, and tractability of genomic analysis. Here we review recent advances in the
Available online 13 November 2009
identification of the contribution of cis- and trans-factors to expression divergence. Whereas cur-
Edited by Stefan Hohmann