文档介绍：journal of pharmacy research 6 (2013) 647e652
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Original Article
Development and in-vivo characterization of novel trans
buccal formulations of Amiloride hydrochloride
J. Ravi Kumar Reddy a,b,*, Y. Indira Muzib c, . Chowdary d
a Research Scholar, Jawaharlal Nehru Technological University, Kakinada, Andhra Pradesh, India
b Assistant Professor, Department of Pharmaceutics, Annamacharya College of Pharmacy, Rajampet, Andhra Pradesh, India
c Department of Pharmaceutics, Sri Padmavati Mahila Visvavidyalayam, Tirupati, Andhra Pradesh, India
d Department of Pharmaceutics, Andhra University, Vishakhapatnam, Andhra Pradesh, India
article info abstract
Article history: Objectives: Formulation development and characterization of novel trans-buccoadhesive
Received 14 March 2013 patches and bilayer tablets of Amiloride hydrochloride (AMHCL) with the objectives to
Accepted 27 April 2013 avoid the first-pass effect, incomplete absorption from GIT, improve the bioavailability,
Available online 21 June 2013