文档介绍：食管癌术前放化疗疗效分析
作者：王珏孙成超吴式张萍林超西
【摘要】 目的探讨术前同步放化疗治疗食管癌的疗效 及围手术期并发症。方法2000年12月至XX年8月，26例 食管癌初治患者，采用常规放射野治疗，肿瘤量40Gy,在放 疗的第1周和第4周均给予常规剂量紫杉醇和钳类化疗2个 疗程，休息4〜6周后手术。结果放化疗并发症主要为骨髓 抑制，肺部损害，食管炎。放化疗组的完全病理缓解率为％, 急性毒副反应仅1〜2级，癌肿局部控制率％,远处转移率％, 3年生存率％, 5年生存率％,无病生存率％。多因素分析显 示影响食管癌生存率的因素有病变长度、肿瘤浸润深度、淋 巴结转移情况。术前放化疗对于手术难度没有增加，术后并 发症主要是肺部并发症。结论应用术前同步放化疗治疗食管 癌是安全的，取得了较好的疗效。
【关键词】食管癌手术放射疗法化学疗法
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