文档介绍：甲基强的松龙冲击法治疗急性脊髓损伤的近期观察
 
 
          作者：胡勇，徐荣明，何贤峰，杨述华，阮永平，马维虎，校佰平，周雷杰
【摘要】   目的 探讨应用大剂量甲基强的松龙(MP)对急性脊髓损伤(ASCI)近期神经功能恢复的影响。方法 2002年8月至2005年8月，对60 例急性脊髓损伤患者，根据伤后时间并按照自愿选择用药原则分为应用MP 治疗 组(A组)，32 例，男18 例，女14 例，平均年龄(±) 岁和未应用MP对照组(B组)，28 例，男16 例，女12 例，平均年龄(±) 岁。伤后8 h以内患者列入大剂量MP治疗组，受伤时间超过8 h的患者列入对照组。以ASIA分级标准进行分级，并比较疗效和并发症。分别于入院时、伤后6周和6个月时对脊髓功能进行评分。结果 MP治疗组(A组)的感觉功能在伤后6周和6个月时均有明显好转，运动功能在伤后6个月时才有明显好转。对照组患者脊髓功能恢复不明显。结论 甲基强的松龙是治疗急性脊髓损伤有效的药物，正确、及时使用MP能够早期促进运动功能的恢复，但未显著增加患者治疗中并发症的发生率。
【关键词】   脊髓损伤；甲基强的松龙；神经功能；并发症
    Abstract：Objective  To investigate the effects of highdose methylprednisolone(MP)on the recovery of neurological functions due to acute spinal cord injury in early   From August 2002 to August 2005，according to the principle of voluntary medication，60 cases of ASCl were divided into MP group(32 cases，male 18 cases，female 12 cases，mean ages ±)，control group(28 cases，male 16 cases，female 14 cases，mean ages ±)，according to the class of the American spinal cord injury institution，patients were graded the curative effect and relative complication of each patient were managing in 8 hours post injury were divided into methylprednisolone group
，Cases managing beyond 8 hours post injury were divided into control functions were evaluated at admission，6 weeks and 6 months after   Sensation