文档介绍：FULL PRESCRIBING INFORMATION: CONTENTS*
WARNING: SERIOUS GASTROINTESTINAL ADVERSE 8 USE IN SPECIFIC POPULATIONS
REACTIONS Pregnancy
1 INDICATIONS AND USAGE Nursing Mothers
2 DOSAGE AND ADMINISTRATION Pediatric Use
Adult Patients Geriatric Use
Patients With Hepatic Impairment Hepatic Impairment
Information for Pharmacists Renal Impairment
3 DOSAGE FORMS AND STRENGTHS 10 OVERDOSAGE
4 CONTRAINDICATIONS 11 DESCRIPTION
Constipation 12 CLINICAL PHARMACOLOGY
History of Severe Bowel or Hepatic Mechanism of Action
Disorders Pharmacodynamics
Lack of Understanding of Patient Pharmacokinetics
Acknowledgement Form 13 NONCLINICAL TOXICOLOGY
Concomitant Use of Fluvoxamine Carcinogenesis, Mutagenesis, Impairment
5 WARNINGS AND PRECAUTIONS of Fertility
Serious Complications of Constipation 14 CLINICAL STUDIES
Ischemic Colitis