文档介绍：胰岛素抵抗糖尿病与冠心病
第一页，共29页
Adapted from World Health Organization. Definition, Diagnosis and Classification of Diabetes Mellitus and its Complications. Geneva: World Health Organization:1999:52.
Criteria for the Diagnosis of Diabetes Mellitus and Hyperglycemia Plasma Glucose Concentration
> (>126)
> (>110) to < (<126)
2-Hour Post Glucose Load
Fasting Glucose
Diabetes Mellitus
Impaired Glucose Tolerance
Impaired Fasting Glucose
> (>200)
> (>140) to < (<200)
Values are mmol/L (mg/dl)
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Developed
Developing
Percent
King H et al. Diabetes Care 1998;21:1414-1431.
World
1995
Prevalence of Diabetes in Adult Population (Aged >20 years) by Year and Region
2000
2025
第三页，共29页
Hospitalization Costs for Chronic Complications of Diabetes in the US
American Diabetes Association. Economic Consequences of Diabetes Mellitus in the US in 1997. Alexandria, VA: American Diabetes Association, 1998:1-14.
Total costs 12 billion US $
CVD accounts for 64% of total costs
Others
Ophthalmic disease
Cardiovascular disease
Renal disease
Neurologic disease
Peripheral vascular disease
第四页，共29页
Annual CHD Deaths per 1000 Persons
Kannel WB, McGee DL. JAMA 1979;241:2035-2038.
Framingham Study: DM and CHD Mortality 20-Year Follow-up
17
8
17
4
Men
Women
DM
Non-DM
第五页，共29页
Ischemic heart disease
% of Deaths
Geiss LS et al. In: Diabetes in America. 2nd ed. 1995; chap 11.
Mortality in People with Diabetes Causes of Death
Other heart disease
Diabetes
Cancer
Stroke
Infection
Other
第六页，共29页
Mortality per 1000 person-years*
*Age-adjusted
Adapted from Gu K et al. Diabetes Care 1998;21:1138-1145.
Mortality Due to Heart Disease in Men and Women with or without Diabetes (US)
Men
Women
Diabetes
No Diabetes
All heart disease
Ischemic heart disease
Men
Women
第七页，共29页
Nondiabetes
Diabetes
*Defined in 1971-1975, fol