文档介绍：ISSN 2229-5054
International Journal of Drug Formulation & Research Mar.-Apr. 2011, Vol. 2(2) 94-110
International Journal of Drug Formulation & Research
GARLIC: A REVIEW
Vineet Singla , Radhika Bhaskar* , Rahul Bhaskar
Department of Pharmaceutical Sciences, Lovely School of Pharmaceutical
Sciences , Chaheru, Phagwara (Punjab)
Abstract
Garlic and its preparations have been widely recognized as an agent for prevention and treatment of cardiovascular
diseases and other metabolic disorders, atherosclerosis, hyperlipidemia, thrombosis, hypertension and
hypoglycemia. This review discusses the possible mechanism of therapeutic actions of garlic, different extraction
procedures along with determination of its constituents, its stability and dissolution method of garlic tablet.
Keywords: Garlic, Stability, Tablet, Alliin. Allicin, Antioxidant, Antimicrobial, Anticancer, Antihyperlipidemia,
Antihypertension and Hypoglycemia.
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ISSN 2229-5054
International Journal of Drug Formulation & Research Mar.-Apr. 2011, Vol. 2(2) 94-110
Introduction
Garlic consists of fresh or pound bulbs of Allium Sativum Linn. (Family Lilliaceae).1
It contains not less than % of alliin (the main constituent present in the garlic), calculated on
the dried basis. Its bulbs are made up of cloves and are wrapped in a white papery sheath with
pungent taste and odour. 2
Synonyms
1) Sanskrit : Rasona, Yavanesta
2) English : Garlic
3) Gujrati : Lasan, Lassun
4) Hindi : Lahasun
5) Punjabi : Lasan
6) Urdu : Lahsan, Seer
7) Spanish : Ajo 3
Constituents present in different garlic preparations: -
2) Garlic homogenate : Allicin
3) Heat treated garlic : Alliin
4) Garlic powder : Alliin
5) Aged garlic extract : S-allyl cystine
6) Steam distilled garlic oil : Diallyl disulfide
7) Oil-macerated/ether-extracted garlic oil : 2-vinyl-4-H-1, 3-dithiin