文档介绍：Protective Effects of Garlic Barbarum Extract Liquid
on Lead Acetate Induced ic Damage in Mice
Bi Ruiming
Department of Animal Science, Heze University,
Heze, the People's Republic of China
E-mail: biruiming@
Abstract—By means of the micronucleus (MN) test of the whole preliminary research demonstrated that, the garlic barbarum
mice bone marrow and fetus liver blood, we studied the extract liquid had distinctive the anti-saltation effect, and had
protective effects of the biological preparation viz. the garlic no the mutagentic activity. The work provided a theoretical
barbarum extract liquid on lead acetate induced ic damage basis for human being resisting the lead pollution in the
of mouse somatic cells. The results showed that ,when the lead environment and improving our own health level.
acetate in the mice raised to 30 mg/kg (1/4 LD50), the frequency
of micronucleus would raise to a high level, and the biological
preparation obviously demonstrated its protective effect on II. MATERIALS AND METHODS
animals. After 7 and 14 days drinking freely the garlic barbarum
extract liquid, the inhibition rate to the incidences of A. Animal Materials
micronucleus were 68% and 49% respectively. The garlic The healthy adult Kunming mice in the closed colony were
barbarum extract liquid also had protective effect on lead acetate used as the s