文档介绍：Nipah Virus Classification via Fractal Dimension &
Shannon Entropy
*Physics and **Biology Departments
CUNY munity College
Todd Holden*, N. Gadura**, E. Cheung*, P. Bayside, NY 11364 USA
Schneider**, G. Tremberger, Jr.*, N. Elham*, D. Contact email: ******@
Sunil*, D. Lieberman*, and T. Cheung*
Abstract—Nipah virus glycoprotein and nucleoprotein parison of human and chimpanzee genomes revealed that it
were studied using fractal dimension and Shannon entropy. The is possible to measure the acceleration rate of the accelerated
nucleotide atomic number fluctuation forms the basis of the regions of the human genome [7]. Fractal analysis of these
phylogeny study. The classification reproduces the main results accelerated regions showed that the differences in fractal
of traditional phylogeny analysis, but with better ability to dimension can be used as a marker of evolution. [8]. Additional
distinguish closely related strains. The fractal dimension implications of evolution and positive selection have been
correlation with the GC pair content in the glycoprotein sequence discussed in recent literature [9].
and di-nucleotide entropy in the nucleoprotein suggests different
evolutionary mechanisms or strategies. Extension to other flu
virus suggests that low fractal dimensionality in the II. METHODS
nucleoprotein sequence could be