文档介绍：Morphometric pattern analysis of basal cell nuclei for
oral cancer screening
Pratik Shah#1, Muthu Rama Krishnan M#2 ,Chandan Chakraborty#3, Ajoy Kumar Ray†4
#School of Medical Science and Technology, Indian Institute of Technology-Kharagpur
Kharagpur, West Bengal, India
1pratik0828@
******@
******@..in (corresponding author)
†Bengal Engineering and Science University
Kolkata, India
4ajoy_ray2004@
Abstract — This work presents a quantitative approach for have risen rapidly especially in the Indian subcontinent [1].
discrimination of Oral Submucous Fibrosis (OSF) to Normal This precancerous lesion converts to squamous cell carcinoma
Oral Mucosa (NOM) in respect to size and shape properties of and malignant transformation rate [2] is in the order of %.
the basal layer, first layer in epithelium. Practically, basal cells Presently, the histopathological diagnosis, by
form the partment of the epithelium, and pathologists, of OSF is based on the subjective evaluation of
therefore changes in the morphometry of basal cells may have epithelial dysplasia. In fact, several authors [3, 4] have
serious implications on future cell behavior, including reported the wide variations between observers in the
malignant transformation according to onco-pathologists subjective evaluation of epithelial dysplasia. In order