文档介绍：Oxidative Damage of Decabromodiphenyl Ether
(BDE209) on the Hepatic Cells of Rat in vitro

Yao Wen-hao, Jiang Ming-di, Hu Qin-qin, Li Ren, Yang Xu*
Laboratory of Environmental Sciences
College of Life Science, Huazhong Normal University
Wuhan 430079, China
*Corresponding author email: ******@nu.

Abstract—Owing to its good flame-retardant effect, (PBDEs) are being produced as flame retardants since the
polybrominated diphenyl ethers (PBDEs) were widely added to early 1970s. There are mercial PBDEs products:
electronic, electrical appliances, as well as textiles and chemical Penta-mix, a blend of tetra–hexa PBDEs; Octa-mix, a blend of
products. Decabromodiphenyl Ether (BDE-209) is one class of hepta–nona PBDEs and Deca-mix, 97% pure deca BDE. They
PBDEs which was most demanded in international market. To
have been found in the aquatic environment since the late
illustrate the possible function of BDE-209 on rat liver, hepatic
cells were expose to BDE-209 with different concentrations (1, 2, 1970s [6-8]. Decabromodiphenyl Ether (BDE-209) is one
4, 8, 16 mg•L-1) in vitro, the contents of malondialdehyde (MDA) class of PBDEs which was most demanded in international
and the levels of DNA-protein crosslinks (DPC) were market. After release into the environment, BDE-209 will be
investigated. The results indicated that: with the BDE-209 t