文档介绍：2010全国肠外肠内营养学术会议论文集 Konturek sJ,Kwiecien Obtulowicz parison of intraduodenal and intravenous administration ofamino acids on gastric secretion inhealthy subjects and patients with duodenal ulcer[J].Gut,1978,19(10):859—864. Tari A,Kamiyasu T,Yonei Y,et K-B receptor in the regulation of gastric acid secretion inrat[J】.Dig Dis Sci,1997,42(9): 1901-1907. 空肠输注必需氨基酸对犬胰腺外分泌的影响夏建福, 余震, 张波, 胡礼【接要】目的观察空肠输注必需氨基酸对健康犬胰腺外分泌的影响,并初步探讨其激素机制。方法6只健康犬建立胰腺外分泌模型,同时行空肠、胃及膀胱造瘘,股静脉插管。模型制成24h后,隔日空肠输注必需氨基酸(实验组)和对照组,于输注前30min(T0)、输注后O-~30min(T1)、30~60min(T2)、60--- 90min(T3)、90~120min(T4)时间段分别收集胰液并测定胰液体积、胰液中淀粉酶、总蛋白和主要电解质浓度,同时检测输注前及后30、60、90、120min时点血浆胆囊收缩素(K)浓度。结果空肠输注苯丙氨酸或色氨酸后犬胰液量、胰淀粉酶及胰蛋白浓度较对照组显著升高(尸<),而各组之间主要电解质浓度差异不显著。与对照组比较,K浓度在30、 60min时点明显升高(尸<),K浓度在30min时点明显升高(P <)。苯丙氨酸组和色氨酸组胰液分泌量、K 浓度变化一致。结论空肠输注必需氨基酸一定程度上可改变胰液分泌,且以苯丙氨酸和色氨酸显著,K浓度刺激胰腺分泌有关。【关键词】必需氨基酸肠道营养胰腺外分泌胆囊收缩素犬 Effect ofjejunal essential amino acids perfusion on pancreat icexocrine secret ion indogs XIA Jianfu,YU Zhen,ZHANG Bo,et a1. (Department ofSurgery,The First Affil iated Hospital ofWenzhou Medical College, Wenzhou 325000,Zhejiang,China) [Abstracts] Objective To investigate the effect of jejunal essential amino acids perfusion on pancreatic exocrine secretion in healthy dogs and the hormonal mechanism that may be Six healthy aduit dogs were operated to establish dogs’pancreatic juice external drainage mode