文档介绍：华中科技大学
硕士学位论文
提高显微成像分辨率关键技术的研究
姓名:傅哲强
申请学位级别:硕士
专业:物理电子学
指导教师:张平
20041026
摘要
自第一台显微镜诞生以来显微成像技术已经广泛的应用于医学生物电子
军事工业等各个它所涵盖的微观领域各种新颖的显微成像技术伴随高科技的应用
正在不断的涌现随着信息技术的飞速发展显微成像技术的研究已经成为一个十分
重要的课题本文以目前较为新型的两种显微成像技术数字显微成像系统和光学相
干层析成像系统为研究对象对于提高显微成像系统的横向分辨率和纵向分辨
率的关键技术展开了深入的研究
本文以显微成像技术的发展概况为先导以该研究领域中的热点激光共焦三维扫
描显微系统的基本原理为例给出了显微系统的横向分辨率和纵向分辨率的概
念在对如何提高显微系统的横向和纵向分辨率的关键技术深入理论分析的基础上
本文提出了利用干涉显微镜为核心并结合数字图像处理测量技术相结合的数字显微镜
来提高显微成像系统的横向分辨率和利用自制凸轮纵向扫描机构的系统来提高显
微成像系统中纵向分辨率的两种方法围绕以上两种方法研制了一套数字显微镜系
统并以为开发平台编写了相应的图像处理软件对菲涅尔微
透镜阵列做了深入的实验研究并给出了提高横向分辨率的试验数据同时还研制了一
套以凸轮扫描机构为核心的实验系统对玻璃试样行了实验获得了微米左右的
分辨率并取得了实用眼检系统的实验数据作为对照
本文就如何提高横向分辨率和纵向分辨率的关键技术做的相关研究对于显微成像
领域的设备改进与广泛应用有着实际价值

关键词数字显微系统横向分辨率纵向分辨率 OCT 数字图像处理

I
Abstract
Since the birth of the first microscope, the microscopy imaging technology has been
widely applied in the microcosmic field that it covered just like medicine, biology,
electronic, military, industry and so on. A lot of novel microscopy imaging technology are
coming forth continuously with the application of high-tech. For the fast development of
information technology, the research on microscopic imaging has e the important
topic all around the world. In this paper, we pleted the embedded research on
key-technology to improving transverse resolution and longitudinal resolution of
microscopy imaging system, which is oriented at the two kinds of new-style microscopy
imaging technology that are digital microscope system and optical coherence tomography
(OCT) as research objects.
The thesis brings out the conception of transverse and longitudinal resolution of
microscope system, following the development survey of microscope imaging technology
as the fore-guidance and with the baasis of the theory of confocal scanning optic
microscopy as example which is the hot point of microscope field. Based on the deep
theoretical research on how to improving transverse resolution and longitudi