文档介绍：益肾温督小复方治疗肾虚督寒型强直性脊柱炎30例临床研究
【摘要】  目的研究益肾温督小复方治疗肾虚督寒型强直性脊柱炎的临床疗效及安全性。方法观察益肾温督小复方治疗组(30例)与柳氮磺胺吡啶对照组(30例)强直性脊柱炎患者治疗前后临床症状、体征和实验室指标的变化。%%,%%(P<);患者的Bath强直性脊柱炎疾病活动指数(BASDAI)、功能指数(BASFI)、测量指数(BASMI)及全身和脊柱疼痛Likert四级积分、中医证候积分、患者和医生的总体评分、晨僵时间、血沉(ESR)、C反应蛋白(CRP)、免疫球蛋白G(IgG)、肿瘤坏死因子α(TNF-α)等均有明显改善(P<),且在主要症状、体征及BASMI、IgG、TNF-α、关节影像学积分等方面治疗组的改善较对照组明显(P<)。安全性检测亦未见明显异常。结论益肾温督小复方治疗肾虚督寒型强直性脊柱炎有效、安全。
【关键词】  益肾温督小复方;强直性脊柱炎;肾虚督寒证;中医疗法
    Abstract:Objective To study the clinical effect and safety of Yishen pound in treatment of ankylosing spondylitis (AS) of kidney deficiency and cold governor vessel type. Methods The diversification of the clinical symptoms, signs and laboratory indicators of ankylosing spondylitis patients in Yishen pound 30 cases of treatment group and sulfasalazine (SASP) 30 cases of control group before and after treatment were observed. Results After treatment, the percentage of ASAS20 standard cases number (%) and the efficacy of TCM syndrome total effective rates of treatment group were % and % respectively, superior to sulfasalazine control group % and % (P<). The patients’ BASDAI, BASFI, the whole body and spine ache Likert level 4 integral, TCM syndromes integral, patients and doctors’ overall score, morning stiffness time, BASMI, ESR, CRP, IgG, TNF-α were