文档介绍:更昔洛韦与阿昔洛韦治疗水痘临床疗效观察
更昔洛韦与阿昔洛韦治疗水痘临床疗效观察
【中图分类号】R511【文献标识码】A【文章编号】1672 一 3783(2011) 10-0066-01
【摘要】目的:观察更昔洛韦与阿昔洛韦治疗水痘的临床疗效。 方法:将82例水痘患者随机分为更昔洛韦治疗组和阿昔洛韦治疗组, 治疗3d,观察疗效。结果:更昔洛韦治疗组显效率为64%,总有效 率为94%;%,总有效率为81. 2%。 P<0. 05,差异有统计学意义。结论:更昔洛韦治疗水痘临床疗效优于 阿昔洛韦。
【关键词】更昔洛韦;阿昔洛韦;水痘
[Abstract] Objective:To observe the clinical efficacy of Ganciclovie and Acyclovir in treating Varicella. Methods:82 cases of Varicella were randomly divided into the treatment of Ganciclovir and Acyclovir. Treat them for three days and then observe their effects. Results:The significant efficiency on the Ganciclovir treatment was 64%, total efficient was 94%, While about the treatment of Acyclovir, the significant efficiency was 53. 1%, total efficient was 81. 2%, P<0. 05, the differences between them have Statistically significant. Conclusion: The clinical efficacy of Ganciclovir treatment is superior to Acyclovir in treatingf the Varicella.
[Keywords] Ganciclovir Acyclovir varicella
水痘是由水痘一带状疱疹病毒(varicella—zoster vires, VZV) 感染引起的经呼吸道传播的一种传染性很强的疾病,以斑疹、丘疹、 疱疹、结痂为其主要特点。水痘的发病高峰在冬季后期和早春,虽有 自限性,但可并发肺炎、肝炎、脑炎等, 关文献报道更昔洛韦与阿昔洛韦均为治疗水痘的有效抗病毒药物
。❷[1-2]❷,本文对其疗效进行对比分析。❷
1资料与方法
1. 1 一般资料 我科2008年10月1日一2010年03月1日共收 治水痘患者82例,知情同意后随机分组,其中更昔洛韦治疗组50例, 男28例,女22例,年龄7月龄〜30岁;阿昔洛韦治疗组32例,男 15例,女17例,年龄10月龄〜32岁。所有患者具有典型水痘皮疹, 发热, —°C, 78%有水痘患者接触史。2组患者平均年 龄、性别、病情差异经检验无统计学意义。
1. 2方法 更昔洛韦组用更昔洛韦5m