文档介绍：吡柔比星膀胱内灌注对减少腺性膀胱炎术后复发的效果及对患者生活质量的影响
 
 
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摘 要 目的：探讨吡柔比星膀胱内灌注对减少腺性膀胱炎术后复发的效果及其对患者生活质量的影响。方法：回顾性分析70例腺性膀胱炎患者的临床资料，根据治疗方法为对照组34例和研究组36例。两组患者均接受经尿道等离子电切术治疗，对照组患者术后给予止血、抗感染、镇痛等治疗，研究组则在对照组的基础上给予吡柔比星膀胱内灌注治疗。比较两组患者的临床疗效、不良反应发生情况以及血清TNF-a和IL-6的水平。随访1年，观察两组患者腺性膀胱炎的复发情况，采用SF-36量表对两组患者的生活质量进行评估。结果：研究组患者治疗的总有效率显著高于对照组（P<）；研究组患者术后的复发率显著低于对照组（
P<）。結论：吡柔比星膀胱内灌注可有效降低腺性膀胱炎患者血清TNF-a和IL-6的水平，降低术后复发的风险，提高患者的生活质量。
关键词 吡柔比星 腺性膀胱炎 生活质量 临床疗效
： ：B ：1006-1533（2017）07-0014-04
Effect of intravesical instillation of pirarubicin on the recurrence of glandular cystitis and the quality of life*
LI Yanmin1，2**， ZHU Jianhua3， XIE Hua3， WU Gengqing1，2（ of Urology， The First Hospital affiliated to Gannan Medical University， Jiangxi Ganzhou 341000， China； 2. Institute of Urology， Gannan Medical University， Jiangxi Ganzhou 341000， China； 3. Department of Urology， Traditional Chinese Medicine Hospital of Nankang District， Jiangxi Ganzhou 341000， China）
ABSTRACT Objective： To discuss the effects of intravesical instillation of pirarubicin on the recurrence of glandular cystitis and the quality of life. Methods： Sixty-eight patients were selected and divided into a control group （n=34） and a research group （n=36）. All the patients were treated with transurethral plasmakinetic resection of the prostate. The control group was treated with hemostasis， antiinfection and analgesia while the research group with intravesical instillation of pirarubicin on the basis of the control group. The clinical effects， adverse reactions and the levels of serum TNF-a and IL-6were compare
d. The recurrence of glandular cystitis was observed after one year follow-up and the quality of life was evaluated by SF-36 scale. Results： The total effective rate in the research group was higher than that in the control group （P<）. The levels of TNF-a and IL-6 at 7 and 14 days after treatment were lower in the research group than in the control group， and the life quali