硫酸氨基葡萄糖联合依托考昔治疗膝骨性关节炎的临床效果.pdf

文档介绍：临床医学研究与实践 2021 年 12 月第 6 卷第 34 期 临床医学
硫酸氨基葡萄糖联合依s (KOA). Atotalof120patientswithKOAweredividedintocontrolgroupandexperimental
groupbythesegmentedrandomizationmethod,
etoricoxib,
Results
ofthetwogroupswerecompared. Thetotaleffectiverateoftreatmentintheexperimentalgroupwashigherthan
P
thatinthecontrolgroup( <).Aftertreatment,thejointfunction,jointstiffness,painscores,WOMACtotalscore,the
levelsofTNF-α,IL-18,IL-17andIL-1β inthetwogroupswerelowerthanthosebeforetreatment,andthoseinthe
P
experimentalgroupwerelowerthanthecontrolgroup( <).Therewasnosignificantdifferenceinthetotalincidence
P Conclusion
ofadversereactionsbetweenthetwogroups ( >). Glucosaminesulfatecombinedwithetoricoxibinthe
treatmentofKOApatientshasasignificanteffect,itcanimprovethekneefunctionandinflammatoryfactorlevels,and
hashighsafety.
KEYWORDS:
etoricoxib;glucosaminesulfate;kneeosteoarthritis
膝骨性关节炎（ ）是 一 种 常见的骨科疾病，属于慢