文档介绍：2 克罗思病中西医研究进展中文摘要克罗恩病(Crohn's disease,CD)是一种病因尚不十分清楚的胃肠道慢性炎性肉芽肿性疾病。临床以腹痛、腹泻、腹块、瘘管形成和肠梗阻为特点,可伴有发热、贫血、营养障碍以及关节、皮肤、眼、口腔粘膜、肝脏等肠外损害。因其病因尚不明确, 迄今尚无能完全治愈cD的有效方法,多数患者常反复发作,迁延不愈。本病以欧美国家常见,亚非国家少见。我国尚缺乏有关cD的确切的流行病学资料,过去认为国内少见,但近年来各地迭有报道,并认为cD的发病率有增高趋势。 cD在中医学中尚无某一病名与其完全相应,古代医籍中的“腹痛”“泄泻“‘积聚”“便血”“肠痈”等与其症状类似。中医学认为本病发病与感受外邪、饮食劳倦、情志内伤、脾胃虚弱等因素密切相关,古代文献及现代研究表明,中医药治疗有较好的疗效。笔者通过对近十几年中西医研究文献进行综述,对本病的西医研究概况有一个较全面的认识;在对中医研究文献进行综述时发现了明显的薄弱点,并针对此提出了一些粗浅的看法,认为若以内痈论治克罗思病可更规范cD的中医诊治。【关键词】:进展克罗恩病中西医 Abstraet Abstract Crohn’sdisease(CD),whose cause is notunknown,is achronic,inflammatory and granulomatous condition ofthegastrointestinal tractclinically characterized by stomachache,diarrhea,abdominal mass,fistulization and bowel obstruction, possibly panying withfever,anemia,nutritional disturbance orextraintestinal impairment injoints,skin,eyes,oral mucosa or liver;for most patients,it is a protracted diseaseand recurrent attackscan oftheunknown cause,up tonow thereis plete healing decades ago,the tendency ofCD’sincidence andprevalence rateinEuropean and North American countries was goingup;but in1980s,it became stable andtheattack rateineach year was 34-106/100, America,the totalnumber ofCD patients was about 50,000 to100,000plus 5,000-10,000 new patients was alackof exact epidemiological dataabout CD thepast,it wBs believed thatCD was rareindomestic;but in recent years there are afewreports insome places andit issaidthatthedisease rateisincreasing. IntraditionalChinesemedicine(TCM),there is no certaindisease thatistotally corresponding toCD;yet itssymptoms are similarwithsome diseases recorded by doctors in ancienttimes such asstomachache,diarrhea,abdominal mass or toTCM,its onset isclosely related tothe attackofexogenous pathogenic factors,improper dietand overtiredness,intemal injury caused by emotions or deficiency ofspleen and stomach;the treatment based on syndrome differentiation isofgood curativeeffe