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ALLERGY
CONTENTS
Preface xi
Anthony Montanaro
ics of Allergic Disease 1
John W. Steinke and Larry Borish
ics provides the basis for the host response to a variety of
environmental factors that can result plex ic diseases,
such as asthma and atopy. An understanding of the ic basis
for these conditions is essential to understand their pathophysiol-
ogy. Several regions of the human genome have been reproducibly
associated with asthma and atopy and the functional effects of the
variation in these regions are being elucidated. It is hoped that
these and ongoing studies will ultimately define new targets for
the next generation of asthma and allergy therapeutics.
Allergic Rhinitis: Impact of the Disease and Considerations
for Management 17
Alexander N. Greiner
Allergic rhinitis is mon yet underappreciated inflammatory
condition of the nasal mucosa. This article reviews current concepts
of classification, the impact of the disease on quality of life, and as-
sociated conditions and provides a detailed account of currently
available treatment options.
Asthma: Diagnosis and Management 39
Sameer K. Mathur and William W. Busse
The diagnosis and management of asthma conti