文档介绍：化工进展
2006 年第 25 卷第 3 期 CHEMICAL INDUSTRY AND ENGINEERING PROGRESS 259
生物碱提取与纯化技术应用进展
喻朝阳王晓琳
清华大学化学工程系北京 100084

摘要生物碱是许多中药的有效成分提取与纯化是生物碱制备的关键环节目前较为常用的提取方法有煎煮
浸渍回流和渗漉纯化方法有有机溶剂萃取色谱和树脂吸附超声微波辅助提取超临界流体萃取分子
印迹和膜分离等技术的应用使生物碱制备向高效节能方向发展本文综述了生物碱制备常用的提取与纯化工艺与
新技术的应用进展分析了它们的原理及优缺点并探讨了发展前景
关键词生物碱提取纯化
中图分类号 TQ 028 文献标识码 A 文章编号 1000– 6613 2006 03– 0259– 05

Progress in extraction and purification of alkaloids

YU Zhaoyang WANG Xiaolin
(Department of Chemical Engineering Tsinghua University Beijing 100084)

Abstract Alkaloids are the effective ingredients in many Chinese herbs. The extraction and purification
technology is the key issue in alkaloid preparation. At present monly used extraction technology
includes decoction circumfluence maceration and percolation. The purification technology anic
solvent extraction adsorption chromatography ion-exchange resin adsorption and macro-porous resin
adsorption. New technologies such as ultrasound microwave supercritical fluid extraction molecular
imprinting and membrane separation technology are used to increase efficiency and save energy of the
extraction and purification process. The methods and the application of new technologies in extracting and
purifying alkaloids are reviewed. Moreover the prospect of alkaloid preparation is discussed.
Key words alkaloid extraction purification