文档介绍：Effects of Experimental Epilepsy on Rats’ Exploring Ability
[Abstract] Objective To find out the effects of experimental epilepsy on exploring ability of rats of different ages. Methods Made epilepsy models of rats by injecting penicillin, then test the rats’ exploring ability using the open field method. Results Numbers of squares crossed by experimental rats increase obviously, but numbers of squares crossed by experimental sucking rats decrease in the late stage of the experiment. Conclusions Adult rats are sensitive to damage of epilepsy, but sucking rats are somewhat immune to damage of epilepsy. Recent damage of exploring ability of sucking rat is reversible.
[Key Words] Exploring Ability Rats Penicillin Open Field Test
Preface
Epilepsy is a chronic disease of the brain characterized by the sudden, repeated and temporary disfunction of central nerve system caused by cerebral neurons’ over-releasing electron. We observe the effects of experimental epilepsy on exploring ability of rats by the open field method.
2 Materials and methods
Selection and grouping of rats:
Divide 20d-rats(P20, sucking rats) and 60d-rats(P60, adult rats) into experimental group and control group at random respectively, each group including 6 rats.
Medicine and equipment:
Penicillin (160000U/mL), equipment of the open field method.
Methods:
The experimental group rats are inj