文档介绍：门冬胰岛素联合甘精胰岛素治疗糖尿病的临床疗效观察[ 摘要] 目的探讨门冬胰岛素联合甘精胰岛素治疗糖尿病的临床疗效。方法将 60例2 型糖尿病( T2DM )患者按照治疗方式分为对照组与观察组各 30 例,对照组采用人胰岛素注射液治疗,观察组采用门冬胰岛素联合甘精胰岛素治疗。比较两组治疗前后血糖水平、胰岛β细胞功能改善情况、胰岛素用量及血糖波动情况、治疗前后患者生活质量评分变化情况。结果①两组治疗后血糖指标( FBG 、 2hPBG 及 HbA1c ) 水平均显著低于治疗前( P< ) ,且观察组治疗后上述指标水平也均显著小于对照组( P< );②两组治疗后胰岛β细胞功能指标( FINS 、 2hINS 、△ I30/ △ G30 及 HOMA β) 水平均显著大于治疗前( P< 或 P< ), 且观察组治疗后上述指标水平也均显著大于对照组治疗后( P< );③观察组治疗后胰岛素用量及血糖波动值均显著小于对照组( P< )。结论门冬胰岛素联合甘精胰岛素治疗糖尿病的临床疗效显著, 可有效改善患者的血糖及胰岛β细胞功能,应在临床上对该方案进行推广。[ 关键词]2 型糖尿病( T2DM ) ;门冬胰岛素;甘精胰岛素;临床疗效[ 中图分类号] [ 文献标识码]B[ 文章编号] 1673-9701 ( 2015 ) 15-0073-03 [Abstract] Objective To investigate the clinical efficacy of insulin aspart bined glargine in treatment of diabetes. Methods A total of 60 patients with type 2 diabetes mellitus ( T2DM ) patients according to treatment were randomly divided into the control group and the observation group , and the control group was given human insulin injection therapy , the observation group was given insulin aspart bined with glargine. Blood glucose levels pared before and after treatment , islet β cell function to improve the situation , the amount of insulin and blood sugar fluctuations , the quality of life in patients with scores before and after treatment were observed pared. Results ① After treatment , glycemic index ( FBG , 2hPBG and HbA1c ) levels were significantly lower than before treatmen