文档介绍：中国呼 吸与危 重监 护杂志 2010 年 11 月第 9 卷第 6 期 Chin J Respir Crit Care Med, November 2010, Vol. 9, No. 6 · 587·
berculosis drugs in 834 cases( 70. 44% ) , and resistant in 350 cases
( 29. 56% ) , in which initial resistance and secondary resistance accounted for 44. 86% ( 157/350) and
55. 14% ( 193 /350) respectively. In 157 cases with initial resistance, 53 cases ( 33. 8% ) were mono-drug
resistant tuberculosis( MonoDR-TB) , of which 38 cases were resistance to Streptomycin( 24. 2% ) ; 72 cases
( 45. 9% ) were polydrug-resistant tuberculosis( PDR-TB) ; 20 cases ( 12. 7% ) were multidrug-resistant
tuberculosis ( MDR-TB) ; 12 cases ( 7. 6% ) were extensively drug resistant tuberculosis ( XDR-TB) . There
was no totally drug-resistant tuberculosis ( TDR-TB) . Conclusions The initial drug resistance of M.
tuberculosis in patients with pulmonary tuberculosis is still serious. Unified management of TB control
programs and full supervision of chemotherapy are very imperative.
【Key words】 Mycobacterium tuberculosis; Drug resistance; Pulmonary tuberculosis
目前, 结核病是严重危害人类健康的传染病, 也 们按照世界卫生组织( WHO) / 国际防痨和肺 部疾病
是全球关注的公共卫 生问 题和 社会 问 题, 随着 各地 联合会( IUATLD) 全球结 核病 耐药 监测 指 南的 统一
耐药监测项目的开展, 耐 多药 病 例及 广泛 耐药 病例 要求, 在住院患者中