文档介绍：・1336 ・ ChineseHepatology, Dec. 2021,Vol. 26,No.
oxidative stress, T lymphatic subsets and liver function indexes were recorded. Results After 4-week treatment , the levels of
serum superoxide dismutase (SOD) , catalase (CAT ) , glutathione peroSdase (GSH-Px) , CD3 + , CD4 + and CD4 + /CD8 + in
observationgroupweresignificantlyincreased whilethelevelsofmalondialdehyde (MDA) andCD 8+ inobservationgroupwere
significantlydecreased (P<).Thelevelsofalanineaminotransferase (ALT) andtotalbilirubin (TBIL) inobservationgroup
weresignificantlylowerthanthoseincontrolgroup (P<).Therewasnosignificantdiferenceinthelevelsofalbumin (ALB)
andfibrinogen (FIB) betweenthe2 groups (P〉).Therewasnosignificantdiferenceinadversedrugreactions (ADR)
betweenthe2groups (P〉) .Conclusion NACcaninhibittheoxidativestresslevel regulatecelularimmunefunctionand
improvetheliverfunctionofHCCpatientsundergoingTACE andithashighsafety.
【Keywords】 Transcatheter arterial chemoembolization% N-acetylcysteine% Oxidative stress% Immune function% Liver
function
肝动脉化疗栓塞术(TACE)后肝内局部高浓度的 免疫功能，抑制炎症应激反应，保护肝细胞膜和改善
化疗药物对肝组织损害，以及栓塞术后肝组织缺血缺 肝功能⑵* N-乙酰半胱氨酸(NAC)可通过调节肝细
氧、促使乙肝病毒(HBV)在肝内复制等原因，均可引