文档介绍：Oral Oncology 46 (2010) 439–441
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Oral Oncology
journal homepage: ate/oraloncology
Review
Advances in radiotherapy for head and neck cancer
. Bhide, . Nutting *
Royal Marsden Hospital and Institute of Cancer Research, London, UK
article info summary
Article history: Radiotherapy and surgery are the principal curative modalities in treatment of head and neck cancer.
Available online 20 April 2010 Conventional (two dimensional, 2D and three-dimensional conformal radiotherapy, 3DCRT) result in sig-
nificant side-effects and altered quality of life. Intensity modulated radiotherapy (IMRT) can spare the
Keywords: normal tissues, while delivering a curative dose to the tumour bearing tissues. Technical advances like
Radiotherapy volumetric intensity modulated arc therapy (VMAT) have helped optimise IMRT further. Image guided
Head and neck cancer radiotherapy (IGRT) can be used to aid target delineation and also help reduce the PTV margins to further
enhance the therapeutic ratio. Particle therapy using protons provides significant advantage in terms of
normal tissue sparing and is mended for small cranial tumours and in radiotherapy for paediatric
patients.
Ó 2010 Elsevier Ltd. All rights reserved.
Introduction and has the ability to produce concavities in radiation treatment
volumes. It allows for greater spari