文档介绍：Int. J. Radiation Oncology Biol. Phys., Vol. 81, No. 5, pp. e833–e838, 2011
Copyright Ó 2011 Elsevier Inc.
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doi:.
CLINICAL INVESTIGATION Head and Neck
INCREASED RISK OF ISCHEMIC STROKE IN YOUNG NASOPHARYNGEAL
CARCINOMA PATIENTS
yk zk yk
CHING-CHIH LEE, .,* ** YU-CHIEH SU, ., ** HSU-CHUEH HO, ., **
xk xk xk
SHIH-KAI HUNG, ., ** MOON-SING LEE, ., ** WEN-YEN CHIOU, ., PESUS CHOU,.,*
{
AND YUNG-SUNG HUANG, .
*Community Medicine Research Center and Institute of Public Health, National Yang-Ming University, Taipei, Taiwan; yDepartment
of Otolaryngology, zDivision of Hematology-Oncology, Department of Internal Medicine, xDepartment of Radiation Oncology,
kTumor Center, {Division of Neurology, Department of Internal Medicine, Buddhist Dalin Tzu Chi General Hospital, Chiayi, Taiwan;
**School of Medicine, Tzu Chi University, Hualien, Taiwan
Purpose: Radiation/chemoradiotherapy-induced carotid stenosis and cerebrovascular events in patients with na-
sopharyngeal carcinoma (NPC) can cause severe disability and even death. This study aimed to estimate the risk of
ischemic stroke in this patient population over more than 10 years of follow-up.
Methods and Materials: The study cohorts consisted of all patients hospitalized with a pr