文档介绍：Int. J. Radiation Oncology Biol. Phys., Vol. 80, No. 4, pp. 1248–1255, 2011
Copyright Ó 2011 Elsevier Inc.
Printed in the USA. All rights reserved
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doi:.
PHYSICS CONTRIBUTION
SMARTARC-BASED VOLUMETRIC MODULATED ARC THERAPY FOR
OROPHARYNGEAL CANCER: A PARISON WITH BOTH
INTENSITY-MODULATED RADIATION THERAPY AND HELICAL TOMOTHERAPY
y
STEFANIA CLEMENTE,.,* BINBIN WU,.,* GIUSEPPE I, .,*
y
VINCENZO FUSCO, ., FRANCESCO HETTI, .,* JOHN WONG,.,*
AND TODD MCNUTT,.*
*Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Baltimore, MD; and yDepartment
of Radiation Oncology, S CROB, Rionero in Vulture, Potenza, Italy
Purpose: To investigate the roles of volumetric modulated arc therapy with SmartArc (VMAT-S), intensity-
modulated radiation therapy (IMRT), and helical tomotherapy (HT) for oropharyngeal cancer using a simulta-
neous integrated boost (SIB) approach.
Methods and Materials: Eight patients treated with IMRT were selected at random. Plans puted for both
IMRTand VMAT-S (using Pinnacle TPS for an Elekta Infinity linac) along with HT. A three-dose level prescription
was used to deliver 70 Gy, 63 Gy, and Gy to regions of macroscopic, microscopic high-risk, and microscopic
low-risk disease, respectively. All doses were g